Curved optics for x-ray phase contrast imaging by synchrotron radiation

Phys Med Biol. 2001 Apr;46(4):967-74.

Abstract

Conventional radiographic techniques have strong limitations when low-absorption contrast samples are imaged. Phase contrast radiography has been shown to produce high-quality images of soft tissues. In this technique the recorded intensity patterns are related to gradients in the refractive index of the sample. A critical point of this new technique is the need to employ crystal analysers, which results in an appreciable reduction in the beam intensity and consequently in rather long exposure times. In this paper the use of focused beams is suggested to overcome this aspect. Biological samples with small structures and low absorption variations were imaged using both flat and curved monochromator crystals, demonstrating that the use of curved optics leads to a decrease in the exposure time with only a limited degradation of the spatial resolution. This opens up the possibility of using the phase contrast technique with laboratory sources.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Butterflies
  • Diagnostic Imaging / instrumentation*
  • Diagnostic Imaging / methods*
  • Microscopy, Phase-Contrast / methods
  • Synchrotrons*
  • Time Factors
  • Tomography, X-Ray Computed / methods*
  • X-Rays