Abstract
Cutaneous T-cell lymphomas are a heterogeneous group of cutaneous non-Hodgkin's lymphomas. In the United States, the incidence of these diseases is rising faster than any other cancer. Environmental triggers may be important in the evolution of malignancy. Current therapy is reviewed with emphasis on a new retinoid, Targretin.
MeSH terms
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Administration, Oral
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Administration, Topical
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Anticarcinogenic Agents / therapeutic use*
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Apoptosis / drug effects
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Bexarotene
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Biopsy
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Carmustine / administration & dosage
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Disease Progression
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Drug Eruptions / etiology
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Humans
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Hypertriglyceridemia / chemically induced
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Lymphoma, T-Cell, Cutaneous / drug therapy*
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Lymphoma, T-Cell, Cutaneous / pathology
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Mechlorethamine / administration & dosage
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Mechlorethamine / adverse effects
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Neoplasm Staging
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PUVA Therapy
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Prognosis
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Retinoids / therapeutic use
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Sezary Syndrome / drug therapy
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Sezary Syndrome / immunology
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Tetrahydronaphthalenes / adverse effects
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Tetrahydronaphthalenes / therapeutic use*
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Vitamin D / therapeutic use
Substances
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Anticarcinogenic Agents
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Retinoids
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Tetrahydronaphthalenes
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Vitamin D
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Mechlorethamine
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Bexarotene
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Carmustine