Aberrant amplification of A(2A) receptor signaling in striatal cells expressing mutant huntingtin

FASEB J. 2001 May;15(7):1245-7.
No abstract available

MeSH terms

  • Adenosine-5'-(N-ethylcarboxamide) / pharmacology
  • Adenylyl Cyclases / metabolism
  • Cell Line
  • Colforsin / pharmacology
  • Corpus Striatum / cytology*
  • Corpus Striatum / metabolism*
  • Cyclic AMP / metabolism
  • Humans
  • Huntingtin Protein
  • Huntington Disease / genetics
  • Huntington Disease / metabolism
  • Kinetics
  • Models, Biological
  • Mutation
  • Nerve Tissue Proteins / chemistry
  • Nerve Tissue Proteins / genetics*
  • Nerve Tissue Proteins / metabolism
  • Nuclear Proteins / chemistry
  • Nuclear Proteins / genetics*
  • Nuclear Proteins / metabolism
  • Purinergic P1 Receptor Antagonists
  • Radioligand Assay
  • Receptor, Adenosine A2A
  • Receptors, Purinergic P1 / genetics
  • Receptors, Purinergic P1 / metabolism*
  • Second Messenger Systems / physiology*
  • Signal Transduction

Substances

  • HTT protein, human
  • Huntingtin Protein
  • Nerve Tissue Proteins
  • Nuclear Proteins
  • Purinergic P1 Receptor Antagonists
  • Receptor, Adenosine A2A
  • Receptors, Purinergic P1
  • Colforsin
  • Adenosine-5'-(N-ethylcarboxamide)
  • Cyclic AMP
  • Adenylyl Cyclases