A convenient method for the efficient removal of ruthenium byproducts generated during olefin metathesis reactions

Org Lett. 2001 May 3;3(9):1411-3. doi: 10.1021/ol010045k.

Abstract

[reaction in text] An efficient method for removing ruthenium byproducts generated during olefin metathesis reactions with Grubbs catalysts is described. Treatment of the crude reaction products with triphenylphosphine oxide or dimethyl sulfoxide, followed by filtration through silica gel, was found to be a practical and effective method to remove colored ruthenium byproducts.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Alkenes / chemistry*
  • Catalysis
  • Dimethyl Sulfoxide / chemistry
  • Malonates / chemistry*
  • Molecular Structure
  • Organophosphorus Compounds / chemistry
  • Ruthenium / chemistry*

Substances

  • Alkenes
  • Malonates
  • Organophosphorus Compounds
  • diethyl diallylmalonate
  • Ruthenium
  • Dimethyl Sulfoxide
  • triphenylphosphine oxide