Analgesic and antiinflammatory activities of vernonioside B2 from Vernonia condensata

Phytother Res. 2001 May;15(3):263-4. doi: 10.1002/ptr.733.

Abstract

Vernonioside B2 isolated from the methanol extract of the Brazilian herb Vernonia condensata Baker was evaluated in vivo for analgesic and antiinflammatory activities. The compound reduced writhings (93.28%) and Evans blue dye diffusion (91.80%) induced by acetic acid (0.1 N) in a dose-dependent manner.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acetic Acid
  • Analgesics / pharmacology
  • Analgesics / therapeutic use*
  • Animals
  • Anti-Inflammatory Agents / pharmacology
  • Anti-Inflammatory Agents / therapeutic use*
  • Asteraceae*
  • Dose-Response Relationship, Drug
  • Glucosides / pharmacology
  • Glucosides / therapeutic use*
  • Male
  • Mice
  • Pain / chemically induced
  • Pain / prevention & control*
  • Pain Measurement / drug effects
  • Plant Extracts / pharmacology
  • Plant Extracts / therapeutic use
  • Plants, Medicinal*

Substances

  • Analgesics
  • Anti-Inflammatory Agents
  • Glucosides
  • Plant Extracts
  • vernonioside B2
  • Acetic Acid