Skin involvement as the first manifestation of systemic aspergillosis in patients after allogeneic hematopoietic cell transplantation

C Schimmelpfennig; R Naumann; T Zuberbier; R Ordemann; H Baurmann; J Beyer; W Siegert; M Bornhäuser; G Ehninger

doi:10.1038/sj.bmt.1702835

Skin involvement as the first manifestation of systemic aspergillosis in patients after allogeneic hematopoietic cell transplantation

Bone Marrow Transplant. 2001 Apr;27(7):753-5. doi: 10.1038/sj.bmt.1702835.

Authors

C Schimmelpfennig¹, R Naumann, T Zuberbier, R Ordemann, H Baurmann, J Beyer, W Siegert, M Bornhäuser, G Ehninger

Affiliation

¹ Medizinische Klinik und Poliklinik I, Universitätsklinikum Carl Gustav Carus an der TU Dresden, Fetscher Str. 74, 01307 Dresden, Germany.

PMID: 11360117
DOI: 10.1038/sj.bmt.1702835

Abstract

Skin involvement due to a systemic infection with Aspergillus species in the course of allogeneic hematopoietic cell transplantation is extremely rare. We report the clinical course of two patients with hematologic malignancies who underwent allogeneic hematopoietic cell transplantation (HCT) and developed disseminated skin involvement as the first clinical symptom of a proven systemic Aspergillus infection.

Publication types

Case Reports

MeSH terms

Adult
Aspergillosis / etiology
Aspergillosis / immunology
Aspergillosis / pathology*
Fatal Outcome
Hematologic Neoplasms / complications
Hematologic Neoplasms / therapy
Hematopoietic Stem Cell Transplantation / adverse effects*
Humans
Immunocompromised Host / physiology
Male
Middle Aged
Necrosis
Skin Diseases / etiology*
Skin Diseases / microbiology
Skin Diseases / pathology
Transplantation, Homologous / adverse effects