Objective: To determine beta-cell's function by measuring blood glucose level and serum insulin level in women who had history of gestational diabetes mellitus (GDM), but had no long-term diabetes.
Methods: 30 cases in GDM history group, 29 cases in abnormal oral glucose tolerance test(OGTT) history group, and 38 cases in control Group were followed up to undergo fasting blood sugar test and 75 g glucose load test, and to measure their insulin levels. All the cases had no long-term diabetes.
Result: (1) the blood glucose levels at 2 hour in GDM history group and abnormal OGTT history group were higher than that in control group especially the former, which was very significantly higher (P < 0.001). (2) The insulin at 2 hours in GDM history group was higher than that in control group (P = 0.00067).
Conclusion: Though women with GDM history do not have long-term diabetes, insulin resistance still exists, postings a possible sign for future diabetes attack.