AIDS: Some reports have suggested that drug-induced hepatotoxicity can be associated with antiretroviral therapy in HIV-positive people coinfected with chronic hepatitis C virus (HCV). Several presentations at the 38th Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) examined this possible interaction. The impact of highly active antiretroviral therapy (HAART) on persons coinfected with HCV was described. There is increasing clinical recognition that HCV can lead to significant liver-related morbidity and mortality among HIV-infected persons.