Detection of human papillomavirus in non-small cell lung carcinoma by polymerase chain reaction

Folia Histochem Cytobiol. 2001;39(2):127-8.

Abstract

Human papillomavirus (HPV) infection is one of the risk factors contributing to the pathogenesis of lung cancer. The aim of the study was to determine the presence of HPV in non-small cell carcinomas of the lung. The study included 40 tumors: 22 squamous cell carcinomas, 13 adenocarcinomas and 5 large cell carcinomas. HPV was found in 4 cases (10%). High risk HPV was present in 3 tumors: in one squamous cell carcinoma, one large cell carcinoma and one adenocarcinoma, while low risk HPV was detected in one adenocarcinoma.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Carcinoma, Non-Small-Cell Lung / virology*
  • DNA, Neoplasm / genetics
  • DNA, Neoplasm / isolation & purification
  • Humans
  • Lung Neoplasms / virology*
  • Papillomaviridae / genetics*
  • Reverse Transcriptase Polymerase Chain Reaction
  • Risk Assessment

Substances

  • DNA, Neoplasm