D:A friedo-oleanane lactones from the stems of Mallotus repandus

J Nat Prod. 2001 May;64(5):569-71. doi: 10.1021/np0005560.

Abstract

Three new D:A-friedo-oleanane lactones, viz., 3-oxo-D:A-friedo-oleanan-27,16alpha-lactone (1), 3alpha-benzoyloxy-D:A-friedo-oleanan-27,16alpha-lactone (2), and 3beta-hydroxy-D:A-friedo-oleanan-27,16alpha-lactone (3) were isolated from the stems of Mallotus repandus. Extensive use of NMR spectroscopic techniques led to full assignment of all 1H and 13C chemical shifts. The structure for 2 was confirmed by X-ray diffraction analysis.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Chromatography, Thin Layer
  • Crystallography, X-Ray
  • Euphorbiaceae / chemistry*
  • Lactones / chemistry
  • Lactones / isolation & purification*
  • Magnetic Resonance Spectroscopy
  • Mass Spectrometry
  • Molecular Conformation
  • Oleanolic Acid / analogs & derivatives
  • Oleanolic Acid / chemistry
  • Oleanolic Acid / isolation & purification*
  • Plant Stems / chemistry
  • Plants, Medicinal / chemistry*
  • Thailand

Substances

  • 3-benzoyloxy-A-friedo-oleanan-27,16-lactone
  • 3-hydroxy-A-friedo-oleanan-27,16-lactone
  • 3-oxo-A-friedo-oleanan-27,16-lactone
  • Lactones
  • Oleanolic Acid