Brachycerine, a novel monoterpene indole alkaloid from Psychotria brachyceras

V A Kerber; T S Gregianini; J T Paranhos; J Schwambach; F Farias; J P Fett; A G Fett-Neto; J A Zuanazzi; J C Quirion; E Elizabetsky; A T Henriques

doi:10.1021/np000590e

Brachycerine, a novel monoterpene indole alkaloid from Psychotria brachyceras

J Nat Prod. 2001 May;64(5):677-9. doi: 10.1021/np000590e.

Authors

V A Kerber¹, T S Gregianini, J T Paranhos, J Schwambach, F Farias, J P Fett, A G Fett-Neto, J A Zuanazzi, J C Quirion, E Elizabetsky, A T Henriques

Affiliation

¹ Faculdade de Farmácia, Universidade Federal do Rio Grande do Sul, Av. Ipiranga 2752, Porto Alegre, RS, CEP: 90 610 000, Brazil.

PMID: 11374976
DOI: 10.1021/np000590e

Abstract

Brachycerine (1), an unusual alkaloid from the leaves of Psychotria brachyceras, was characterized through spectroscopic data interpretation and its stereochemistry established by NOE difference techniques. Brachycerine (1) was found to be restricted to shoots in rooted cuttings of P. brachyceras (0.018 +/- 0.004% dry weight), and accumulation was unaffected by root induction treatment with auxin.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Brazil
Chromatography, High Pressure Liquid
Indoles / chemistry*
Indoles / isolation & purification
Magnetic Resonance Spectroscopy
Monoterpenes*
Plant Leaves / chemistry
Plant Stems / chemistry
Plants, Medicinal / chemistry*
Rubiaceae / chemistry*
Spectrophotometry, Ultraviolet
Terpenes / chemistry*
Terpenes / isolation & purification

Substances

Indoles
Monoterpenes
Terpenes
brachycerine