Automation and high through-put for a DNA database laboratory: development of a laboratory information management system

M Steinlechner; W Parson

Automation and high through-put for a DNA database laboratory: development of a laboratory information management system

Croat Med J. 2001 Jun;42(3):252-5.

Authors

M Steinlechner¹, W Parson

Affiliation

¹ Institute of Legal Medicine, University of Innsbruck, Muellerstrasse 44, A-6020 Innsbruck, Austria. [email protected]

PMID: 11387633

Abstract

Automation and high through-put production of DNA profiles has become a necessity in every DNA database unit. In our laboratory we developed a Laboratory Information Management System (LIMS) controlled workflow architecture, which comprises a robotic DNA extraction- and pipetting-system and a capillary electrophoresis unit. This allows a through-put of 4,000 samples per person per year. Improved sample handling and data management, full sample- and batch-histories, and software-aided supervision of result data, with a consequent average turn-around time of 8 days, are the main features of our new system.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Austria
Clinical Laboratory Information Systems / standards*
DNA Fingerprinting / methods*
Database Management Systems / standards*
Electronic Data Processing / methods*
Forensic Medicine / methods*
Humans
Sensitivity and Specificity