Management of idiopathic thrombocytopenic purpura in children: a single institution experience

Pediatr Med Chir. 2000;22(1):31-4.

Abstract

Idiopathic thrombocytopenic purpura (ITP) is a relatively common hematologic disease in childhood. ITP is often self-limiting and is characterized by a good clinical outcome. About 10-20% of cases can have a chronic course. In our retrospective analysis we have evaluated 45 patients affected by ITP from January '92 to December '97. Thirty-seven patients (82%) met the criteria of acute ITP and 8 (18%) had chronic ITP. Patients were stratified into 3 categories based up on the type of treatment received: no treatment, steroids, steroids and IVIG. In our series children treated with oral prednisone showed a slightly faster recovery in the first days from treatment. We suggest the use of steroids in children with low platelet count and signs and symptoms of bleeding.

MeSH terms

  • Child
  • Child, Preschool
  • Female
  • Humans
  • Male
  • Purpura, Thrombocytopenic, Idiopathic / drug therapy*
  • Retrospective Studies