Abstract
Efg1 is essential for hyphal development in the human pathogen Candida albicans under most conditions. Efg1 is related to basic helix-loop-helix regulators, and therefore most workers presume that Efg1 is a transcription factor. Here we confirm that Efg1 is a DNA binding protein that can interact specifically with the E box.
Publication types
-
Research Support, Non-U.S. Gov't
MeSH terms
-
Binding Sites
-
Candida albicans / cytology*
-
Candida albicans / genetics*
-
DNA-Binding Proteins / metabolism*
-
Fungal Proteins*
-
Genes, Fungal
-
Promoter Regions, Genetic
-
Protein Binding
-
Transcription Factors / metabolism*
Substances
-
DNA-Binding Proteins
-
EFG1 protein, Candida albicans
-
Fungal Proteins
-
Transcription Factors