Thrombolysis of extracranial and intracranial arteries after IV abciximab

E Houdart; F Woimant; R Chapot; C Mounayer; C Soria; J J Merland

doi:10.1212/wnl.56.11.1582

Thrombolysis of extracranial and intracranial arteries after IV abciximab

Neurology. 2001 Jun 12;56(11):1582-4. doi: 10.1212/wnl.56.11.1582.

Authors

E Houdart¹, F Woimant, R Chapot, C Mounayer, C Soria, J J Merland

Affiliation

¹ Department of Neuroradiology and Therapeutic Angiography, Hôpital Lariboisière, Paris, France. [email protected]

PMID: 11402122
DOI: 10.1212/wnl.56.11.1582

Abstract

Abciximab was administered intravenously to three patients to treat thrombus associated with atherosclerotic stenosis of a supra-aortic artery. In two cases, the thrombi had been identified on a previous angiography more than a week before treatment. Successful thrombolysis was achieved with abciximab in all three cases. In this small series, abciximab had a thrombolytic effect on established thrombi that were refractory to previous antithrombotic treatment attempts.

Publication types

Case Reports

MeSH terms

Abciximab
Antibodies, Monoclonal / administration & dosage*
Anticoagulants / administration & dosage*
Cerebral Angiography
Female
Humans
Immunoglobulin Fab Fragments / administration & dosage*
Injections, Intravenous
Intracranial Arteriosclerosis / diagnosis
Intracranial Arteriosclerosis / therapy
Intracranial Thrombosis / diagnosis
Intracranial Thrombosis / therapy*
Male
Middle Aged
Thrombolytic Therapy*

Substances

Antibodies, Monoclonal
Anticoagulants
Immunoglobulin Fab Fragments
Abciximab