A preliminary study on the analgesic activity of Grangea maderaspatana

Fitoterapia. 2001 Jun;72(5):553-4. doi: 10.1016/s0367-326x(00)00326-9.

Abstract

The methanol extract of the whole plant of Grangea maderaspatana showed a dose-dependent analgesic activity. At doses of 1 and 3 g/kg, the extract significantly (P<0.001) inhibited acetic acid-induced writhing in mice by 50 and 80%, respectively.

MeSH terms

  • Acetic Acid / adverse effects
  • Analgesics, Non-Narcotic / administration & dosage
  • Analgesics, Non-Narcotic / pharmacology*
  • Analgesics, Non-Narcotic / therapeutic use
  • Animals
  • Asteraceae*
  • Dose-Response Relationship, Drug
  • Male
  • Mice
  • Pain / chemically induced
  • Pain / prevention & control*
  • Pain Measurement / drug effects*
  • Plant Extracts / administration & dosage
  • Plant Extracts / pharmacology
  • Plant Extracts / therapeutic use
  • Plants, Medicinal*

Substances

  • Analgesics, Non-Narcotic
  • Plant Extracts
  • Acetic Acid