Short-TE projection reconstruction NMR microscopy of trabecular bone

R Toffanin; V Jellús; P Szomolányi; F Vittur

doi:10.1016/s0730-725x(01)00273-9

Short-TE projection reconstruction NMR microscopy of trabecular bone

Magn Reson Imaging. 2001 Apr-May;19(3-4):485-6. doi: 10.1016/s0730-725x(01)00273-9.

Authors

R Toffanin¹, V Jellús, P Szomolányi, F Vittur

Affiliation

¹ Department of Biochemistry, Biophysics and Macromolecular Chemistry, University of Trieste, Trieste, Italy. [email protected]

PMID: 11445336
DOI: 10.1016/s0730-725x(01)00273-9

Abstract

The aim of this study was to assess the potential of projection reconstruction (PR) NMR microscopy in the quantitative evaluation of trabecular bone architecture. Short-TE PR spin-echo microimages were acquired at 7.05 T on normal bone explants. The main structural parameters such as bone volume fraction (BVF), trabecular thickness (Tb.Th.) and trabecular separation (Tb.Sp.) were obtained from the 3D microimages using the method of directed secants. Quantitative structural data were then compared with those derived from conventional spin-echo microimages. Our study indicates that projection reconstruction NMR microscopy promises to be more accurate than the conventional FTI method in the analysis of trabecular bone.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
Bone and Bones / chemistry*
Magnetic Resonance Imaging / methods*
Swine