Abstract
Removal of the pineal gland leads to structural and functional rearrangement of gastric endocrine cells and thyroid C-cells in albino rats, as was shown by immunohistological methods and morphometry. Injection of pineal peptides epithalone and epithalamine eliminated these changes. Biological activity of epithalone is believed to be higher than that of epithalamine.
Publication types
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Comparative Study
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English Abstract
MeSH terms
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APUD Cells / cytology
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APUD Cells / drug effects
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APUD Cells / physiology*
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Animals
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Male
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Oligopeptides / pharmacology
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Peptides / pharmacology
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Peptides / physiology*
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Pineal Gland / physiology*
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Rats
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Rats, Wistar
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Thyroid Gland / cytology
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Thyroid Gland / drug effects
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Thyroid Gland / physiology*
Substances
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Oligopeptides
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Peptides
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epithalamin
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alanyl-glutamyl-aspartyl-glycine