Successful testing protocols in virology

Clin Chem. 2001 Aug;47(8):1559-62.

Abstract

Molecular methods have had a significant impact on the diagnosis of viral infections because of their superior sensitivity and rapid turnaround time compared with conventional diagnostic methods. These characteristics have allowed molecular tests to play a central role in the use of testing protocols for managing viral infections. Several examples of such protocols are reviewed in this report, including the use of molecular testing for early disease detection to improve overall disease management and to direct antiviral therapy.

Publication types

  • Review

MeSH terms

  • Antiviral Agents / administration & dosage
  • Antiviral Agents / therapeutic use
  • Cytomegalovirus / genetics
  • Cytomegalovirus Infections / diagnosis
  • Cytomegalovirus Infections / drug therapy
  • Cytomegalovirus Infections / etiology
  • Drug Resistance, Microbial
  • Genotype
  • HIV Infections / drug therapy
  • HIV Infections / virology
  • HIV-1 / genetics
  • Hepacivirus / genetics
  • Hepatitis C / drug therapy
  • Hepatitis C / virology
  • Humans
  • Organ Transplantation / adverse effects
  • Polymerase Chain Reaction
  • Randomized Controlled Trials as Topic
  • Virology / methods*
  • Virus Cultivation
  • Virus Diseases* / diagnosis
  • Virus Diseases* / drug therapy
  • Virus Diseases* / virology

Substances

  • Antiviral Agents