Volume-localized two-dimensional correlated magnetic resonance spectroscopy of human breast cancer

M A Thomas; N Binesh; K Yue; N DeBruhl

doi:10.1002/jmri.1170

Volume-localized two-dimensional correlated magnetic resonance spectroscopy of human breast cancer

J Magn Reson Imaging. 2001 Aug;14(2):181-6. doi: 10.1002/jmri.1170.

Authors

M A Thomas¹, N Binesh, K Yue, N DeBruhl

Affiliation

¹ Department of Radiological Sciences, University of California, Los Angeles, California 90095-1721, USA. [email protected]

PMID: 11477678
DOI: 10.1002/jmri.1170

Abstract

A localized 2D correlation spectroscopic sequence (L-COSY) was implemented and applied in human breast cancer in vivo to evaluate the water to fat (both saturated and unsaturated) ratios and also to identify choline. Being in agreement with the conventional 1D magnetic resonance spectroscopy (MRS) results, elevated water to lipids ratios were found in breast cancers and choline was observed only in a few cancer patients.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Adult
Breast / pathology
Breast Neoplasms / diagnosis*
Case-Control Studies
Female
Humans
Magnetic Resonance Spectroscopy* / methods
Middle Aged