Objective: To seek for the effective traditional Chinese medicine (TCM) replenishing recipe (RR) prescription that being able to prevent the onset of oxygen convulsion and to offer some clues in preventing the oxygen convulsion with TCM-RR.
Methods: Mice were administered orally with four respective representative RR, Sijunzi Decoction, Siwu Decoction, Liuwei Dihuang Decoction, and Renshen Dihuang Decoction. Then the convulsion latent periods were recorded and SOD vitalities in brain and lung were determined.
Results: Compared with the control groups, the convulsion latent period of Sijunzi Decoction group was prolonged significantly (P < 0.01) and its SOD vitality in lung was maintained higher (P < 0.01) after convulsion, while the other three RR results have no significant difference (P < 0.05).
Conclusion: Sijunzi Decoction has certain preventive effect on acute oxygen convulsion.