Objective: To evaluate the expression of growth factor receptors (GFRs) on lung cancer cells and the relation between the expression of GFRs and metastasis of lung cancer.
Method: The expression of EGFR, PDGFR and IGF-1R was detected with immunohistochemical method using monoclonal antibodies.
Result: The expression of EGFR, PDGFR and IGF-1R showed higher positive rates in lung cancer cells than those in normal lung tissues, and the expression was increased as the disease was advanced.
Conclusion: The increased expression of EGFR, PDGFR and IGF-1R is related with the metastasis of lung cancer.