Neurostimulation of the ventral intermediate thalamic nucleus in inherited myoclonus-dystonia syndrome

Mov Disord. 2001 Jul;16(4):769-71. doi: 10.1002/mds.1119.

Abstract

We report on the effects of bilateral neurostimulation of the ventral intermediate thalamic nucleus (VIM) in a patient with medically intractable and progressing inherited myoclonus dystonia syndrome (IMDS). Postoperatively, the patient improved by approximately 80% on the modified version of a myoclonus score without any significant change in the dystonic symptoms. This suggests that neurostimulation of the VIM may be an effective treatment for myoclonus in pharmacologically intractable IMDS.

Publication types

  • Case Reports

MeSH terms

  • Brain Mapping
  • Dominance, Cerebral / physiology
  • Dystonic Disorders / genetics
  • Dystonic Disorders / physiopathology
  • Dystonic Disorders / therapy*
  • Electric Stimulation Therapy*
  • Humans
  • Male
  • Middle Aged
  • Myoclonus / genetics
  • Myoclonus / physiopathology
  • Myoclonus / therapy*
  • Neurologic Examination
  • Ventral Thalamic Nuclei / physiopathology*