Breast cancer in two sisters with Friedreich's ataxia

Eur J Surg Oncol. 2001 Aug;27(5):512-4. doi: 10.1053/ejso.2000.1093.

Abstract

Friedreich's ataxia (FRDA) is an autosomal recessive neurodegenerative disorder causing progressive ataxia and dysarthria. We report two sisters who had breast cancer aged 39 years and 42 years and who both developed a late onset form of FRDA with onset of neurological symptoms in their thirties. We discuss whether there may be an association between the late onset form of FRDA and malignancy.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adult
  • Breast Neoplasms / genetics*
  • Female
  • Friedreich Ataxia / complications*
  • Humans