Occupational exposure to carbon black and risk of bladder cancer

Lancet. 2001 Aug 18;358(9281):562. doi: 10.1016/S0140-6736(01)05717-8.

Abstract

Exposure to carbon black has been linked to risk of lung and bladder cancer. We therefore investigated the frequency of these cancers in a group of 2286 longshoremen who were exposed occupationally to carbon-black dust. We identified 208 cancers (standardised incidence ratio 96, 95% CI 83-109), 53 lung cancers (108, 81-141), and 32 bladder cancers (130, 89-184). Longshoremen exposed to high concentrations of carbon black (n=14) had a significantly increased frequency of bladder cancer (204, 112-343). We conclude that the increase in bladder cancer in longshoremen is probably related to high exposure to carbon black.

Publication types

  • Letter

MeSH terms

  • Adult
  • Air Pollutants, Occupational / adverse effects*
  • Carbon / adverse effects*
  • Humans
  • Incidence
  • Italy / epidemiology
  • Male
  • Occupational Diseases / epidemiology*
  • Occupational Diseases / etiology*
  • Occupational Exposure / adverse effects*
  • Poisson Distribution
  • Registries
  • Retrospective Studies
  • Urinary Bladder Neoplasms / epidemiology*
  • Urinary Bladder Neoplasms / etiology*

Substances

  • Air Pollutants, Occupational
  • Carbon