Squamous cell carcinoma in situ arising in inflammatory cloacogenic polyps: report of two cases with PCR analysis for HPV DNA

R C Jaworski; S A Biankin; P J Baird

Squamous cell carcinoma in situ arising in inflammatory cloacogenic polyps: report of two cases with PCR analysis for HPV DNA

Pathology. 2001 Aug;33(3):312-4.

Authors

R C Jaworski¹, S A Biankin, P J Baird

Affiliation

¹ Department of Tissue Pathology, Institute of Clinical Pathology and Medical Research, Westmead Hospital, New South Wales, Australia.

PMID: 11523931

Abstract

Inflammatory cloacogenic polyp (ICP) is regarded as part of the spectrum of pathological changes encountered in mucosal prolapse syndrome (MPS)/solitary rectal ulcer. We present the clinicopathological features of two females with squamous cell carcinoma in situ arising in their ICPs. Human papillomavirus (HPV) type 16 was demonstrated in the areas of squamous carcinoma in situ in both polyps by polymerase chain reaction. These cases highlight the need for close scrutiny of the squamous components of these lesions.

Publication types

Case Reports

MeSH terms

Adult
Anus Neoplasms / pathology*
Anus Neoplasms / virology
Carcinoma in Situ / pathology*
Carcinoma in Situ / virology
Carcinoma, Squamous Cell / pathology*
Carcinoma, Squamous Cell / virology
Colonic Polyps / pathology*
Colonic Polyps / virology
DNA, Viral / analysis
Female
Humans
Neoplasms, Second Primary / pathology*
Neoplasms, Second Primary / virology
Papillomaviridae / genetics
Papillomaviridae / isolation & purification
Papillomavirus Infections / complications
Papillomavirus Infections / pathology
Polymerase Chain Reaction
Rectal Prolapse / complications
Rectal Prolapse / pathology
Syndrome
Tumor Virus Infections / complications
Tumor Virus Infections / pathology
Ulcer / complications
Ulcer / pathology

Substances

DNA, Viral