Primary central nervous system T-cell lymphoma

Neurology. 2001 Aug 28;57(4):716-8. doi: 10.1212/wnl.57.4.716.

Abstract

Most primary CNS lymphomas (PCNSL) are B-cell neoplasms; T-cell lymphomas are quite rare. The authors report two young patients with T-cell PCNSL who had a complete response to chemo- and radiotherapy but developed recurrent disease and died 11 and 13 months from diagnosis. The prognosis of T-cell PCNSL may be worse than that of comparable B-cell tumors.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Antimetabolites, Antineoplastic / therapeutic use
  • Central Nervous System Neoplasms / diagnosis*
  • Central Nervous System Neoplasms / drug therapy
  • Central Nervous System Neoplasms / radiotherapy
  • Cytarabine / therapeutic use
  • Fatal Outcome
  • Humans
  • Lymphoma, T-Cell / diagnosis*
  • Lymphoma, T-Cell / drug therapy
  • Lymphoma, T-Cell / radiotherapy
  • Male
  • Methotrexate / therapeutic use
  • Neoplasm Recurrence, Local / pathology
  • Prognosis

Substances

  • Antimetabolites, Antineoplastic
  • Cytarabine
  • Methotrexate