Functional brain mapping of monkey tool use

Neuroimage. 2001 Oct;14(4):853-61. doi: 10.1006/nimg.2001.0878.

Abstract

When using a tool, we can perceive a psychological association between the tool and the body parts-the tool is incorporated into our "body-image." During tool use, visual response properties of bimodal (tactile and visual) neurons in the intraparietal area of the monkey's cerebral cortex were modified to include the hand-held tool. Visual properties of the monkey intraparietal neurons may represent the body-image in the brain. We explored tool use-induced activation within the intraparietal area and elsewhere in alert monkey brain using positron emission tomography (PET). Tool use-related activities compared with the control condition (simple-stick manipulation) revealed a significant increase in cerebral blood flow in the corresponding intraparietal region, basal ganglia, presupplementary motor area, premotor cortex, and cerebellum. These tool use-specific areas may participate in maintaining and updating the body-image for the precise guidance of a hand-held rake onto a distant reward.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Brain / blood supply
  • Brain / physiology*
  • Brain Mapping*
  • Image Processing, Computer-Assisted
  • Imaging, Three-Dimensional
  • Macaca
  • Male
  • Parietal Lobe / blood supply
  • Parietal Lobe / physiology*
  • Problem Solving / physiology
  • Psychomotor Performance / physiology*
  • Regional Blood Flow / physiology
  • Tomography, Emission-Computed*