Abstract
This study was conducted to investigate whether a single dose of nebulized budesonide effectively decreased airway inflammation as demonstrated by exhaled nitric oxide (eNO) levels. A single dose of nebulized budesonide, but not nebulized terbutaline, rapidly decreased eNO levels in 6 hours. The decrease in eNO levels induced by nebulized budesonide was correlated to an increase in peak expiratory flow rate.
Publication types
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Clinical Trial
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Randomized Controlled Trial
MeSH terms
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Adolescent
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Asthma / drug therapy*
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Blood Pressure / drug effects
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Bronchodilator Agents / administration & dosage
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Bronchodilator Agents / therapeutic use*
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Budesonide / administration & dosage
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Budesonide / therapeutic use*
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Case-Control Studies
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Child
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Female
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Humans
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Male
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Nebulizers and Vaporizers
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Nitric Oxide / metabolism*
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Peak Expiratory Flow Rate / drug effects
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Terbutaline / administration & dosage
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Terbutaline / pharmacology*
Substances
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Bronchodilator Agents
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Nitric Oxide
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Budesonide
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Terbutaline