Abstract
Symptomatic adrenal insufficiency, presenting as hypoglycaemia or poor weight gain, may occur on withdrawal of corticosteroid treatment but has not previously been reported during inhaled corticosteroid treatment. This case series illustrates the occurrence of clinically significant adrenal insufficiency in asthmatic children while patients were on inhaled corticosteroid treatment and the unexpected modes of presentation. General practitioners and paediatricians need to be aware that this unusual but acute serious complication may occur in patients treated with inhaled corticosteroids.
MeSH terms
-
Administration, Inhalation
-
Administration, Topical
-
Adrenal Insufficiency / chemically induced*
-
Adrenal Insufficiency / diagnosis
-
Adrenocorticotropic Hormone
-
Androstadienes / adverse effects
-
Anti-Inflammatory Agents / adverse effects*
-
Asthma / complications
-
Asthma / drug therapy*
-
Beclomethasone / adverse effects
-
Budesonide / adverse effects
-
Child
-
Child, Preschool
-
Female
-
Fluticasone
-
Humans
-
Hydrocortisone / blood
-
Hydrocortisone / urine
-
Male
Substances
-
Androstadienes
-
Anti-Inflammatory Agents
-
Budesonide
-
Adrenocorticotropic Hormone
-
Fluticasone
-
Beclomethasone
-
Hydrocortisone