Late recurrence of a primitive neuro-ectodermal tumor

Oncology. 2001;61(3):189-91. doi: 10.1159/000055373.

Abstract

Late recurrences after therapy are rare in primitive neuro-ectodermal tumor (PNET). Most recurrences occur within the first 2 years after therapy, although a small number of recurrences may occur up to 5 years after therapy. We present a rare case of a recurrence of PNET in a 31-year-old woman 17 years after her initial presentation. The potential biological implications of this late recurrence as well as responses to subsequent therapy, including temozolomide, are discussed.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Alkaline Phosphatase / analysis
  • Antineoplastic Agents, Alkylating / therapeutic use
  • Biomarkers, Tumor / analysis
  • Cerebellar Neoplasms / drug therapy
  • Cerebellar Neoplasms / secondary*
  • Cerebellar Neoplasms / surgery
  • Cervical Vertebrae*
  • Chemotherapy, Adjuvant
  • Cisplatin / administration & dosage
  • Cyclophosphamide / administration & dosage
  • Dacarbazine / analogs & derivatives*
  • Dacarbazine / therapeutic use
  • Dura Mater*
  • Female
  • Humans
  • Isoenzymes / analysis
  • Lumbosacral Region
  • Meningeal Neoplasms / drug therapy
  • Meningeal Neoplasms / radiotherapy
  • Meningeal Neoplasms / secondary*
  • Neoplasm Proteins / analysis
  • Neuroectodermal Tumors, Primitive / drug therapy
  • Neuroectodermal Tumors, Primitive / radiotherapy
  • Neuroectodermal Tumors, Primitive / secondary*
  • Phosphopyruvate Hydratase / analysis
  • Pinealoma / pathology*
  • Pinealoma / radiotherapy
  • Radiosurgery
  • Remission Induction
  • Sciatica / etiology
  • Spinal Neoplasms / drug therapy
  • Spinal Neoplasms / radiotherapy
  • Spinal Neoplasms / secondary*
  • Synaptophysin / analysis
  • Temozolomide
  • Time Factors
  • Vincristine / administration & dosage

Substances

  • Antineoplastic Agents, Alkylating
  • Biomarkers, Tumor
  • Isoenzymes
  • Neoplasm Proteins
  • Synaptophysin
  • Vincristine
  • Dacarbazine
  • Cyclophosphamide
  • Alkaline Phosphatase
  • Phosphopyruvate Hydratase
  • Cisplatin
  • Temozolomide