Abstract
Penile urethral swabs collected from PCR-confirmed Chlamydia trachomatis-infected, C. trachomatis-uninfected, and non-C. trachomatis-infected, nongonococcal urethritis-infected males were analyzed for cytokine, total immunoglobulin (Ig), and specific antibody levels by enzyme-linked immunosorbent assay. Differential cellular components of the swab transport medium were also enumerated for the same groups. Although low, the levels of C. trachomatis-specific IgA and IgG antibodies and interleukin 8 cytokine were significantly higher in C. trachomatis-infected individuals. There were no significant differences in the levels of seven additional cytokines evaluated.
Publication types
-
Research Support, U.S. Gov't, P.H.S.
MeSH terms
-
Adolescent
-
Adult
-
Antibodies, Bacterial / analysis
-
Chlamydia Infections / blood
-
Chlamydia Infections / immunology*
-
Chlamydia Infections / pathology
-
Chlamydia trachomatis / genetics
-
Chlamydia trachomatis / immunology*
-
Cytokines / analysis*
-
Humans
-
Immunoglobulin A / analysis
-
Immunoglobulins / analysis
-
Interleukin-8 / analysis
-
Lymphocyte Count
-
Male
-
Middle Aged
-
Proteinase Inhibitory Proteins, Secretory
-
Proteins / metabolism
-
Th1 Cells / immunology
-
Th2 Cells / immunology
-
Urethra / immunology*
-
Urethra / pathology
-
Urethral Diseases / blood
-
Urethral Diseases / immunology*
-
Urethral Diseases / pathology
Substances
-
Antibodies, Bacterial
-
Cytokines
-
Immunoglobulin A
-
Immunoglobulins
-
Interleukin-8
-
Proteinase Inhibitory Proteins, Secretory
-
Proteins