Response of metastatic epidermoid anal cancer to single agent irinotecan: a case report

Tumori. 2001 Jan-Feb;87(1):58-9. doi: 10.1177/030089160108700113.

Abstract

We report a case of a patient affected by epidermoid anal cancer who had hepatic progression after standard therapy with the Nigro regimen (fluorouracil and mitomycin C plus radiotherapy). This is an uncommon neoplasm against which only few chemotherapeutic agents have been tested. In our patient salvage treatment with low dose irinotecan resulted in a partial response.

Publication types

  • Case Reports

MeSH terms

  • Antineoplastic Agents, Phytogenic / therapeutic use*
  • Anus Neoplasms / drug therapy*
  • Anus Neoplasms / pathology
  • Camptothecin / analogs & derivatives*
  • Camptothecin / therapeutic use*
  • Carcinoma, Squamous Cell / drug therapy*
  • Carcinoma, Squamous Cell / secondary
  • Female
  • Humans
  • Irinotecan
  • Middle Aged
  • Treatment Outcome

Substances

  • Antineoplastic Agents, Phytogenic
  • Irinotecan
  • Camptothecin