Sequoiatones C-f, constituents of the redwood endophyte Aspergillus parasiticus

A A Stierle; D B Stierle; T Bugni

doi:10.1021/np010022e

Sequoiatones C-f, constituents of the redwood endophyte Aspergillus parasiticus

J Nat Prod. 2001 Oct;64(10):1350-3. doi: 10.1021/np010022e.

Authors

A A Stierle¹, D B Stierle, T Bugni

Affiliation

¹ Department of Chemistry and Geochemistry, Montana Tech of the University of Montana, Butte, MT 59701, USA. [email protected]

PMID: 11678666
DOI: 10.1021/np010022e

Abstract

Aspergillus parasiticus, a fungal isolate from a coast redwood tree (Sequoia sempervirens), has been shown to produce four new compounds, sequoiatones C-F (1-4). The structures of these compounds, all of which are cytotoxic to brine shrimp, were deduced by spectral analysis.

Publication types

Comparative Study
Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

Animals
Artemia / drug effects
Aspergillus / chemistry*
California
Cycadopsida / chemistry*
Heterocyclic Compounds, 2-Ring / chemistry
Heterocyclic Compounds, 2-Ring / isolation & purification*
Heterocyclic Compounds, 2-Ring / pharmacology
Magnetic Resonance Spectroscopy
Molecular Structure
Spectrophotometry, Infrared
Spectrophotometry, Ultraviolet
Structure-Activity Relationship
Toxicity Tests

Substances

Heterocyclic Compounds, 2-Ring
sequoiatone C
sequoiatone D
sequoiatone E
sequoiatone F