BipA is required for growth of Escherichia coi K12 at low temperature

P L Pfennig; A M Flower

doi:10.1007/s004380100559

BipA is required for growth of Escherichia coi K12 at low temperature

Mol Genet Genomics. 2001 Oct;266(2):313-7. doi: 10.1007/s004380100559.

Authors

P L Pfennig¹, A M Flower

Affiliation

¹ Department of Microbiology and Immunology, University of North Dakota School of Medicine and Health Sciences, Grand Forks 58202-9037, USA.

PMID: 11683274
DOI: 10.1007/s004380100559

Abstract

The bipA gene encodes a ribosome-associated GTPase postulated to be involved in regulatory functions in enteropathogenic Escherichia coli. Previous studies demonstrated that BipA is tyrosine phosphorylated in EPEC strains, but not in E. coli strain K12. Results presented here indicate that BipA function is required at low temperatures in E. coli K12, suggesting a regulatory role independent of phosphorylation and of pathogenicity.

Publication types

Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

Cell Division / genetics
Escherichia coli / enzymology
Escherichia coli / genetics*
Escherichia coli / growth & development
Escherichia coli Proteins / genetics
Escherichia coli Proteins / physiology*
GTP Phosphohydrolases / genetics
GTP Phosphohydrolases / physiology*
Gene Expression Regulation, Bacterial
Genetic Complementation Test
Mutation
Phenotype
Phosphoproteins*
Plasmids / genetics
Repressor Proteins / genetics
Temperature
Transformation, Genetic

Substances

Escherichia coli Proteins
Phosphoproteins
Repressor Proteins
GTP Phosphohydrolases
typA protein, E coli