Abstract
We investigated the interleukin (IL-4) levels in BALB/c mice immunized with Anisakis extract in single or multiple doses and in mice orally infected with a larva. From animals immunized maximum responses were obtained with the multiple doses with an only IL-4 peak. Conversely, in the mice inoculated with a larva per os, the IL-4 levels showed two peaks of different rates.
MeSH terms
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Animals
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Anisakiasis / immunology
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Anisakiasis / metabolism*
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Anisakis / immunology
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Anisakis / metabolism*
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Antigens, Helminth / immunology
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Antigens, Helminth / metabolism
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Enzyme-Linked Immunosorbent Assay
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Immunoglobulin G / biosynthesis
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Interleukin-4 / biosynthesis*
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Interleukin-4 / blood
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Larva / immunology
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Mice
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Mice, Inbred BALB C
Substances
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Antigens, Helminth
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Immunoglobulin G
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Interleukin-4