Genomic organization and chromosomal mapping of the basic helix-loop-helix factor OUT (Tcf23/TCF23)

Cytogenet Cell Genet. 2001;94(1-2):23-5. doi: 10.1159/000048776.

Abstract

The genomic organization of Tcf23, the gene coding for mouse OUT, a basic helix-loop-helix transcription factor, was determined and its chromosome location was assigned to the A3 region of chromosome 5. By in silico searching, we further found the human counterpart of the mouse OUT gene (TCF23) in the draft human genome sequence and assigned it to 2p24-->p23.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acid Sequence
  • Animals
  • Basic Helix-Loop-Helix Transcription Factors
  • Chromosomes, Human, Pair 2 / genetics*
  • Exons / genetics*
  • Helix-Loop-Helix Motifs*
  • Humans
  • In Situ Hybridization, Fluorescence
  • Introns / genetics
  • Mice
  • Molecular Sequence Data
  • Physical Chromosome Mapping*
  • Sequence Homology, Nucleic Acid
  • Transcription Factors / chemistry
  • Transcription Factors / genetics*

Substances

  • Basic Helix-Loop-Helix Transcription Factors
  • TCF23 protein, human
  • Tcf23 protein, mouse
  • Transcription Factors

Associated data

  • GENBANK/AB059396
  • GENBANK/AB059397