Psoriasis. Immunopathology and immunomodulation

Dermatol Clin. 2001 Oct;19(4):649-57, viii. doi: 10.1016/s0733-8635(05)70306-5.

Abstract

Biologics in development for the treatment of moderate to severe plaque-type psoriasis are discussed in this article. Immunomodulators used as therapeutic, pathogenic probes will continue to identify targets that play primary roles in the pathogenesis of psoriasis.

Publication types

  • Review

MeSH terms

  • Antibodies, Monoclonal / therapeutic use*
  • Cytokines / immunology
  • Humans
  • Immunosuppressive Agents / therapeutic use*
  • Psoriasis / drug therapy*
  • Psoriasis / immunology*
  • Skin / immunology
  • T-Lymphocytes / immunology

Substances

  • Antibodies, Monoclonal
  • Cytokines
  • Immunosuppressive Agents