[Clinic intervention study on urogenital mycoplasma infection of pregnant women]

Zhonghua Liu Xing Bing Xue Za Zhi. 2001 Aug;22(4):293-5.
[Article in Chinese]

Abstract

Objective: To explore the hypothesis of pathogenic relationship between urogenital mycoplasma infection and adverse perinatal outcomes.

Methods: Four hundred and eighty-eight mycoplasma-positive pregnant women detected by culture method were randomly divided into erythromycine-intervention group and non-intervention group. Comparison was made on rate of reverse sero-conversion, of vertical transmission to mycoplasma and adverse perinatal outcomes incidence between groups.

Results: Ureaplasma urealyticum sero-conversion rate and rate of vertical-transmission in intervention group were significantly lower than in non-intervention group (P < 0.05). The incidences rates of preturm labor, post partum fever, puerperal infection and neonate pneumonia in intervention group were significantly lower than in non-intervention group (P < 0.05).

Conclusion: Erythromycin is effective in control of ureaplasma urealyticum infection among pregnant women through cutting off vertical transmission passway and lowering adverse perinatal outcomes against ureaplasma urealyticum.

Publication types

  • Clinical Trial
  • English Abstract
  • Randomized Controlled Trial

MeSH terms

  • Anti-Bacterial Agents / therapeutic use*
  • Erythromycin / therapeutic use*
  • Female
  • Female Urogenital Diseases / drug therapy*
  • Female Urogenital Diseases / microbiology
  • Humans
  • Infectious Disease Transmission, Vertical
  • Mycoplasma Infections / drug therapy*
  • Mycoplasma Infections / microbiology
  • Mycoplasma Infections / transmission
  • Perinatal Care
  • Pregnancy
  • Pregnancy Complications / drug therapy*
  • Treatment Outcome

Substances

  • Anti-Bacterial Agents
  • Erythromycin