Intrathecal clonidine for controlling spastic hypertonia

O Rémy-Néris; P Denys; B Bussel

Intrathecal clonidine for controlling spastic hypertonia

Phys Med Rehabil Clin N Am. 2001 Nov;12(4):939-51, ix.

Authors

O Rémy-Néris¹, P Denys, B Bussel

Affiliation

¹ Department of Physical Medicine and Rehabilitation, Hopital Raymond Poinçaré Garches, France.

PMID: 11723871

Abstract

Intrathecal clonidine is a powerful antispastic drug. Its mechanism of action is more selective than baclofen. The acute effects are reviewed. An assessment of side effects of clonidine during chronic infusion is needed.

Publication types

Review

MeSH terms

Adrenergic alpha-Agonists / administration & dosage
Adrenergic alpha-Agonists / pharmacology*
Adrenergic alpha-Agonists / therapeutic use
Animals
Clonidine / administration & dosage
Clonidine / pharmacology*
Clonidine / therapeutic use
Humans
Injections, Spinal
Muscle Spasticity / drug therapy*
Muscle Spasticity / etiology
Reflex, Stretch / drug effects
Spinal Cord Injuries / complications

Substances

Adrenergic alpha-Agonists
Clonidine