Brain metastases in paediatric solid tumours

Forum (Genova). 2001 Jan-Mar;11(1):75-86.

Abstract

Brain metastases in children with cancer are rare and their incidence is significantly lower (5-10%) than that reported in adults. The development of metastatic brain tumours in children is usually a manifestation of advanced disease and commonly occur after, or at the time of progression at other sites. This review summarises the salient clinical features of the most common paediatric solid tumours that metastasize to the brain including neuroblastoma, musculoskeletal sarcomas, germ cell tumours and melanoma.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Brain Neoplasms / physiopathology*
  • Brain Neoplasms / secondary*
  • Brain Neoplasms / therapy
  • Child
  • Germinoma / physiopathology*
  • Germinoma / secondary*
  • Germinoma / therapy
  • Humans
  • Melanoma / physiopathology*
  • Melanoma / secondary*
  • Melanoma / therapy
  • Neuroblastoma / physiopathology*
  • Neuroblastoma / secondary*
  • Neuroblastoma / therapy
  • Sarcoma / physiopathology*
  • Sarcoma / secondary*
  • Sarcoma / therapy