The cream dilution gene, responsible for the palomino and buckskin coat colours, maps to horse chromosome 21

M M Locke; L S Ruth; L V Millon; M C Penedo; J D Murray; A T Bowling

doi:10.1046/j.1365-2052.2001.00806.x

The cream dilution gene, responsible for the palomino and buckskin coat colours, maps to horse chromosome 21

Anim Genet. 2001 Dec;32(6):340-3. doi: 10.1046/j.1365-2052.2001.00806.x.

Authors

M M Locke¹, L S Ruth, L V Millon, M C Penedo, J D Murray, A T Bowling

Affiliation

¹ Veterinary Genetics Laboratory, University of California, Davis, CA, USA. [email protected]

PMID: 11736803
DOI: 10.1046/j.1365-2052.2001.00806.x

Abstract

The colour locus historically referred to as C in the horse is linked to microsatellites markers on horse chromosome 21. Preliminary results demonstrated linkage of Ccr, thought to be the cream dilution variant of the C locus, to HTG10. An analysis of horse chromosome 21 using additional families confirmed and established a group of markers linked to Ccr. This work also improved the resolution of previously reported linkage maps for this chromosome. Linkage analysis unambiguously produced the map order: SGCV16-(19.1 cM)-HTG10-(3.8 cM)-LEX60/COR73-(1.3 cM)-COR68-(4.5 cM)- Ccr-(11.9 cM)-LEX31. Comparative and synteny data suggested that the horse C locus is not tyrosinase (TYR).

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
Chromosome Mapping / veterinary*
Female
Hair Color / genetics*
Horses / genetics*
Male
Microsatellite Repeats