Expression of the gene encoding the LIM protein CRP2: a developmental profile

J Histochem Cytochem. 2002 Jan;50(1):107-11. doi: 10.1177/002215540205000112.

Abstract

Members of the cysteine-rich protein (CRP) family are evolutionarily conserved Lin-11, Isl-1, Mac-3 (LIM) domain proteins that have been implicated in cell differentiation. Here we describe the expression pattern of the CRP family member CRP2 in mouse. Unlike other CRP family members, which are expressed primarily in muscle, CRP2 is more broadly expressed. In addition to expression in vascular smooth muscle cells, we also detect CRP2-specific transcripts in mesenchymal derivatives and several epithelia.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Amino Acid Sequence
  • Animals
  • Blotting, Northern
  • Embryo, Mammalian / anatomy & histology
  • Embryo, Mammalian / metabolism
  • Embryonic and Fetal Development
  • In Situ Hybridization
  • Mice
  • Molecular Sequence Data
  • Nuclear Proteins*
  • Organ Specificity
  • Proteins*
  • Proto-Oncogene Proteins c-myc / genetics
  • Proto-Oncogene Proteins c-myc / metabolism*
  • Sequence Homology, Amino Acid

Substances

  • Nuclear Proteins
  • Proteins
  • Proto-Oncogene Proteins c-myc
  • cysteine-rich protein, mammalian