Abstract
In this paper we report a rare association of a splenic marginal zone B-cell lymphoma with villous lymphocytes and a T-cell large granular lymphocytic leukemia coexpressing CD4 and CD8 as well as CD56 and CD57 natural killer-associated markers in an asymptomatic patient investigated because of an occasional finding of erythrocytosis and leukocytosis in routine blood analysis. We also discuss the possible reasons for this particular association.
Publication types
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Case Reports
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Research Support, Non-U.S. Gov't
MeSH terms
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Aged
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Blood Cells / pathology
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CD4 Antigens / analysis
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CD56 Antigen / analysis
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CD57 Antigens / analysis
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CD8 Antigens / analysis
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Gene Rearrangement, B-Lymphocyte
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Gene Rearrangement, T-Lymphocyte
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Humans
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Immunophenotyping
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Leukemia, T-Cell / classification
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Leukemia, T-Cell / complications*
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Leukemia, T-Cell / diagnosis
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Lymphocytes / pathology
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Lymphoma, B-Cell / complications*
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Lymphoma, B-Cell / diagnosis
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Lymphoma, B-Cell / genetics
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Male
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Neoplasms, Multiple Primary / complications*
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Neoplasms, Multiple Primary / diagnosis
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Neoplasms, Multiple Primary / genetics
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Polycythemia / complications*
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Spleen / pathology
Substances
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CD4 Antigens
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CD56 Antigen
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CD57 Antigens
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CD8 Antigens