Intramuscular fat content and genetic variants at fatty acid-binding protein loci in Austrian pigs

J Anim Sci. 2001 Nov;79(11):2798-804.

Abstract

Intramuscular fat is an important meat quality trait in pig production. Previously, genetic variants of the heart fatty acid-binding protein (H-FABP) gene and the adipocyte fatty acid-binding protein (A-FABP) gene were suggested to be associated with intramuscular fat content. The objective of this investigation was to study these associations in the three most important Austrian breeding populations (Piétrain, Large White, and Landrace). Restriction fragment length polymorphism analysis of the H-FABP gene revealed a new MspI polymorphic site and genetic variation in all three breeds. Microsatellite analysis of the A-FABP locus showed up to nine different microsatellite alleles segregating. In Austrian breeds, no significant influence of the A-FABP and H-FABP gene polymorphisms on intramuscular fat could be detected. We also evaluated possible associations between the genetic variations at the H-FABP and A-FABP loci and other growth and carcass traits (average daily gain, feed conversion ratio, lean meat content, pH values, meat color, and drip loss). With regard to the extent of the effects, these genetic markers cannot be recommended for selection on growth and carcass traits in Austrian breeding populations.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adipocytes / metabolism
  • Adipocytes / physiology
  • Adipose Tissue / anatomy & histology*
  • Adipose Tissue / metabolism
  • Animals
  • Carrier Proteins / genetics*
  • Carrier Proteins / metabolism
  • Carrier Proteins / physiology
  • Fatty Acid-Binding Proteins
  • Female
  • Gene Expression Regulation
  • Gene Frequency
  • Genetic Markers
  • Genetic Variation
  • Genotype
  • Heart / physiology
  • Male
  • Meat / standards*
  • Muscle, Skeletal / anatomy & histology*
  • Muscle, Skeletal / metabolism
  • Myocardium / metabolism
  • Neoplasm Proteins*
  • Polymerase Chain Reaction / veterinary
  • Polymorphism, Genetic
  • Polymorphism, Restriction Fragment Length
  • Swine / anatomy & histology
  • Swine / genetics*

Substances

  • Carrier Proteins
  • Fatty Acid-Binding Proteins
  • Genetic Markers
  • Neoplasm Proteins