Acquired crossed aphasia in dextral children revisited

Brain Lang. 2001 Dec;79(3):426-43. doi: 10.1006/brln.2001.2499.

Abstract

In contrast to the estimated low incidence of crossed aphasia in dextral adults (among 1%), crossed aphasia in children has been considered a common finding for almost a century. However, reviewing the literature on crossed aphasia in dextrals (CAD) and its related topics from 1975 onward, we encountered only 5 children in a corpus of 180 cases (2.7%). Critical analysis rendered three of the reported cases ambiguous and hence not suitable to draw potentially relevant conclusions. In this review, the neurobehavioral manifestations of the two representative childhood CAD cases are analyzed and compared with adult CAD and acquired childhood aphasia (ACA). In the light of our findings, which support the position of innate cerebral specialization for language, the long-standing controversy as to whether lateralized hemispheric specialization for language is innate or develops progressively during maturation is briefly discussed.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Aphasia / diagnosis*
  • Aphasia / physiopathology*
  • Brain / physiopathology*
  • Child
  • Child, Preschool
  • Female
  • Functional Laterality / physiology*
  • Humans
  • Male
  • Neuropsychological Tests
  • Severity of Illness Index