Case report: primary human herpesvirus-6 associated with an afebrile seizure in a 3-week-old infant

J Med Virol. 2002 Mar;66(3):384-7. doi: 10.1002/jmv.2156.

Abstract

We describe a 3-week-old male infant with an afebrile seizure in whom serologic and polymerase chain reaction (PCR) findings support concomitant primary human herpesvirus 6 (HHV-6) infection. Although HHV-6 infection has been associated with first-time febrile seizures and encephalitis in both immunocompetent and immunocompromised hosts, it has not been associated previously with afebrile seizures in healthy infants. This report provides additional evidence of the neuropathogenic potential of HHV-6.

Publication types

  • Case Reports
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Female
  • Follow-Up Studies
  • Herpesvirus 6, Human / genetics
  • Herpesvirus 6, Human / isolation & purification*
  • Humans
  • Infant, Newborn
  • Male
  • Roseolovirus Infections / blood
  • Roseolovirus Infections / complications
  • Roseolovirus Infections / virology*
  • Seizures / blood
  • Seizures / complications
  • Seizures / virology*