Laboratory confirmation of meningococcal disease in Scotland, 1993-9

J Clin Pathol. 2002 Jan;55(1):32-6. doi: 10.1136/jcp.55.1.32.

Abstract

Aims: To describe the laboratory confirmation of meningococcal disease, using culture and non-culture based techniques, between 1993 and 1999 as part of a national service in Scotland.

Methods: Samples from patients with suspected meningococcal disease in Scotland were analysed by culture and non-culture based techniques to gain a laboratory confirmation of disease. Data were analysed to establish the number of disease cases, the serogroups of the organisms involved, and the importance of the techniques used.

Results: Between 1993 and 1999, there was a total of 1749 notified cases of meningococcal disease in Scotland. Culture based methods provided a laboratory confirmation of 788 cases whereas non-culture techniques confirmed 461 cases.

Conclusions: Non-culture techniques were a useful addition to culture based techniques in Scotland and improved the dataset required for public health management, disease surveillance, and vaccine policy.

MeSH terms

  • Agglutination Tests / methods
  • Antibodies, Bacterial / blood
  • Bacterial Typing Techniques / methods
  • Bacteriological Techniques / methods
  • Humans
  • Incidence
  • Meningococcal Infections / diagnosis*
  • Meningococcal Infections / epidemiology
  • Neisseria meningitidis / classification
  • Neisseria meningitidis / immunology
  • Neisseria meningitidis / isolation & purification
  • Pharynx / microbiology
  • Polymerase Chain Reaction
  • Scotland

Substances

  • Antibodies, Bacterial