Genomic analyses of microbial virulence

Curr Opin Microbiol. 2002 Feb;5(1):27-32. doi: 10.1016/s1369-5274(02)00281-3.

Abstract

Genomic sequencing of bacterial pathogens is providing an increasing wealth of new data. It is, however, still unclear how this information can be used to develop new experimental approaches. Here, we describe recent efforts to complement existing bacterial genetics with genomic methods for the study of pathogenesis.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Bacteria / genetics*
  • Bacteria / pathogenicity*
  • Computational Biology
  • DNA Transposable Elements
  • Gene Expression
  • Oligonucleotide Array Sequence Analysis
  • Sequence Analysis, DNA / methods
  • Virulence

Substances

  • DNA Transposable Elements