Objective: To study the morphology of hepatic angiomyolipoma (HAML).
Methods: HE staining, PAS staining, immunohistochemistry and electronic microscopy were used to study 10 cases from our department and 4 cases from consultation.
Results: All 14 HAML cases showed perivascular epithelioid cells (PEC) with 4 different types of morphology. They presented characteristic PAS positivity premelanosome like structures and dense body under electronic microscopy. Immunohistochemistry demonstrated positive reaction for both actin and HMB45.
Conclusion: Light and electronmicroscopic features and immunophenotype of HAML are characteristic of PEC related lesion.